Moderate to severe Thalassemia can lead to various complications due to chronic anemia and the treatments required to manage the condition. Here are some possible complications:
Iron Overload
Frequent blood transfusions, a common treatment for Thalassemia, can lead to iron overload, where excess iron accumulates in the body.
Bone Deformities and Osteoporosis
Especially in the face and skull due to overactive bone marrow trying to produce more red blood cells.
Infections
People with Thalassemia, particularly those who have had their spleen removed, are at increased risk of infections due to a compromised immune system. Regular vaccinations and preventive antibiotics may be necessary.
Enlarged Spleen
The spleen may become enlarged as it works harder to filter out damaged red blood cells. Increased Anemia as the spleen destroys red blood cells more quickly. If the spleen becomes too large, there is a risk of rupture.
